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Jonathan Barratt

Professor
Department of Infection
University of Leicester
United Kingdom

Biography

PhD I am a Reader in the Department of Infection Immunity & Inflammation at the University of Leicester and an Honorary Consultant Nephrologist in the John Walls Renal Unit, Leicester General Hospital. I qualified from Manchester University Medical School in 1992 with Honours and undertook my clinical training in Manchester, Leeds and Leicester. My PhD focused on the interaction between IgA and the glomerular mesangial cell and my postdoctoral research has characterised a number of important pathogenic pathways in IgA nephropathy. My research group has interests in lymphocyte homing and B cell activation, IgA1 O-glycosylation, elucidation of the 3-dimensional structure of IgA1 and development of tubulointerstitial scarring in IgA nephropathy. I am on the steering committee and treasurer of the International IgA Nephropathy Network and was a member of the group that developed the Oxford Classification of IgA Nephropathy. I am also actively involved in clinical trials in kidney disease and I am a member of the UK Glomerulonephritis Clinical Study Group, UK Kidney Research Consortium and NIHR UK Clinical Research Network Renal Specialty Group. PhD I am a Reader in the Department of Infection Immunity & Inflammation at the University of Leicester and an Honorary Consultant Nephrologist in the John Walls Renal Unit, Leicester General Hospital. I qualified from Manchester University Medical School in 1992 with Honours and undertook my clinical training in Manchester, Leeds and Leicester. My PhD focused on the interaction between IgA and the glomerular mesangial cell and my postdoctoral research has characterised a number of important pathogenic pathways in IgA nephropathy. My research group has interests in lymphocyte homing and B cell activation, IgA1 O-glycosylation, elucidation of the 3-dimensional structure of IgA1 and development of tubulointerstitial scarring in IgA nephropathy. I am on the steering committee and treasurer of the International IgA Nephropathy Network and was a member of the group that developed the Oxford Classification of IgA Nephropathy. I am also actively involved in clinical trials in kidney disease and I am a member of the UK Glomerulonephritis Clinical Study Group, UK Kidney Research Consortium and NIHR UK Clinical Research Network Renal Specialty Group.

Research Interest

Our group are interested in a number of aspects of the pathogenesis of this common glomerulonephritis. We host a number of undergraduate and postgraduate students, Academic Foundation doctors, Academic Clinical Fellows and Academic Lecturers and are always happy to be contacted by clinicians and scientists wishing to develop an interest in research in kidney disease.

Publications

  • Greer MR, Barratt J, Harper SJ, Allen AC, Feehally J. The nucleotide sequence of the IgA1 hinge region in IgA nephropathy.Nephrol Dial Transplant 1998: 13, 1980-1983.

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