Biomedical Sciences
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Biomedical Sciences Experts

Richard Evans


Department of Molecular and Cell Biology
University of Leicester
United Kingdom

Biography

professor

Research Interest

Molecular basis of properties of P2X receptors for ATP P2X receptors for ATP are ligand gated cation channels that comprise a distinct family of ligand gated cation channels with two transmembrane domains, intracellular amino and carboxy termini and a large extracellular ligand binding loop. Seven P2X receptor genes have been cloned (P2X1-7) and they form functional homo-and heteromeric channels with a range of phenotypes.

Publications

  • Roberts JA and Evans RJ. (2007). Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors. J. Neurosci. 27, 4072-4082.

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