Chemical Engineering

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Mark Searle

University of Nottingham
United Kingdom


Searle obtained his B.A. and M.A. in Chemistry from the University of Oxford in 1983 and 1985 respectively. His Ph.D. from the MRC, National Institute for Medical Research, Mill Hill, London followed in 1986. Three years as an Australian Research Council (ARC) Research Fellow preceded his return to the UK as a SERC/GLAXO Research Fellow in Cambridge from 1990 until 1995. In 1995, Dr. Searle was appointed as a Lecturer in Organic Chemistry at the University of Nottingham and promoted through the ranks to full Professor of Biological Chemistry in 2003, serving as Head of School of Chemistry from 2005 to 2013.He is based within the Nottingham Centre for Biomolecular Sciences on the University Park Campus.

Research Interest

Searle has an extensive track record in biophysics and structural biology, having published >150 peer reviewed papers (h-index 36; March 2014). His research interests span fundamental studies of protein-ligand interactions, protein-protein recognition in ubiquitin-mediated signal transduction, autophagy and bone disease, quadruplex nucleic acid structure and recognition, regulation of RNA translation, and protein-protein interactions linked to cell adhesion, contact activation and inflammatory response.

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