Dr Craig Hughes
Lecturer in Cardiovascular Biology
Institute of Cardiovascular & Metabolic Research (ICMR)
University of Reading
United Kingdom
Biography
Dr. Craig Hughes is currently working as a Lecturer in Cardiovascular Biology in the Department of Institute of Caediovascular & Metabolic Research (ICMR), University of Reading , United Kingdom. His research interests includes Understanding signal transduction in platelets, and how this contributes to platelet activation, thrombosis and haemostasis Identifying novel kinase substrates Discovery of the fish collagen receptor (G6f-like). Member of the Molecular & Cellular Medicine Group Impact, Enterprise and Outreach: • Furthering the understanding of how platelets are activated • Outreach for the British Heart Foundation (BHF volunteers day) Esteem Factors: • Peer reviewer for Journal of Thrombosis and Haemostasis, Thrombosis Research, Platelets, andScientific Reports • Book chapter: 'GPVI and CLEC-2'. In 'Platelets, 3rd Edition' (Michelson AD, ed), Academic Press/Elsevier Science (2013) National Collaborators: • Prof. Steve Watson - University of Birmingham • Dr. Mike Tomlinson - University of Birmingham • Dr. Chris O'Callaghan - University of Oxford • Dr. Cédric Ghevaert - University of Cambridge International Collaborators: • Prof. Wilfried Ellmeier - Medical University of Vienna
Research Interest
Understanding signal transduction in platelets, and how this contributes to platelet activation, thrombosis and haemostasis Identifying novel kinase substrates Discovery of the fish collagen receptor (G6f-like)
Publications
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Alshehri, O. M., Hughes, C. E., Montague, S., Watson, S. K., Frampton, J., Bender, M., (2015) and Watson, S. P. "Fibrin activates GPVI in human and mouse platelets" Blood, 126 (13). pp. 1601-1608. ISSN 0006-4971 doi: 10.1182/blood-2015-04-641654
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Di, Y., Mckinnon, T., O'Callaghan, C. and Watson, S. (2017) Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: a novel mechanism of haemostasis. Platelets. ISSN 0953-7104 (In Press)
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Lombard, S., Pollitt, A., Hughes, C., Di, Y., Mckinnon, T., O'Callaghan, C., (2017) and Watson, S. "Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: a novel mechanism of haemostasis"