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Dr Nandini Vasudevan

Associate Professor in Endocrinology
Department of Biological Sciences
University of Reading
United Kingdom

Biography

Dr. Nandini Vasudevan is currently working as a Associate Professor in Endocrinology in the Department of Biological Sciences, University of Reading , United Kingdom. Major Responsibilities: Associate Professor in Endocrinology • Director of Outreach • Supervision of research done by post-graduate and undergraduate students. • Undergraduate advising. • Mentorship of Post-Doctoral Research Fellows. • Teaching of General Endocrinology and Methods in Neuroscience. Research: Neuroendocrinology and Molecular Endocrinology with an emphasis on behaviour using physiologically relevant model systems. • Mechanisms of estrogen action in neuronal cells, including an emphasis on non-genomic and non-transcriptional signalling and their relevance to behaviour. • Mechanisms by which GPR30, a putative membrane Estrogen Receptor (mER) signals in neurons and the relevance to behaviour. • Role of locally synthesized steroids and their relevance to social behaviors. • Role of thyroid hormones in the regulation of anxiety and cognition. Member of the Molecular & Cellular Medicine Group Esteem Factors: • Was PI on a NSF CAREER (USA) grant "Role of nongenomic estrogen signaling in neuromorphology and behavior (April 2011- Dec 2015; 1 million USD). • Co-investigator on NIH R01 Grant "Short term estradiol in middle age: implications for female cognitive aging" (2012-2017; 1,388,365 USD; PI: Dr. Daniels). • Reviewer for endocrine and molecular endocrine journals. • Reviewer for National Science Foundation (NSF), USA grants. International Collaborators: • Dr Kiran Soma, University of British Columbia, Canada • Dr Jeffrey Tasker, Tulane University, USA, • Dr Jill Daniels, Tulane University, USA. • Dr Sonoko Ogawa, Tsukuba University, Japan. • Dr Shinji Tsukuhara, Tsukuba University, Japan. • Dr Gary Dohanich, Tulane University, USA.

Research Interest

Research: Neuroendocrinology and Molecular Endocrinology with an emphasis on behaviour using physiologically relevant model systems. • Mechanisms of estrogen action in neuronal cells, including an emphasis on non-genomic and non-transcriptional signalling and their relevance to behaviour. • Mechanisms by which GPR30, a putative membrane Estrogen Receptor (mER) signals in neurons and the relevance to behaviour. • Role of locally synthesized steroids and their relevance to social behaviors. • Role of thyroid hormones in the regulation of anxiety and cognition.

Publications

  • Clark, S., Pollard, K., Rainville, J. and Vasudevan, N. (2015) Detection of the phosphorylation of the estrogen receptor alpha as an outcome of GPR30 activation. In: Eyster, K. M. (ed.) Estrogen receptors: methods and protocols. Methods in Molecular Biology, 1366. Humana Press, New York, pp. 457-470. ISBN 9781493931262 doi: 10.1007/978-1-4939-3127-9_36

  • Fisher, M. and Vasudevan, N. (2015) Cognition and anxiety are regulated by thyroid hormone signaling. Immunology‚ Endocrine and Metabolic Agents in Medicinal Chemistry, 15 (1). pp. 60-70. ISSN 1875-5844 doi: 10.2174/187152221501150710130829

  • Hadjimarkou, M. M. and Vasudevan, N. (2017) GPER1/GPR30 in the brain: crosstalk with classical estrogen receptors and implications for behavior. Journal of Steroid Biochemistry and Molecular Biology. ISSN 0960-0760 doi: 10.1016/j.jsbmb.2017.04.012 (In Press)

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