Dr Sandrine Claus
Associate Professor
Institute of Cardiovascular & Metabolic Research (ICMR)
University of Reading
United Kingdom
Biography
Dr. Sandrine Claus is currently working as a Associate Professor in the Department of Institute of Caediovascular & Metabolic Research (ICMR), University of Reading , United Kingdom. Her research interests includes My research focuses on the host-gut microbial metabolic interactions in order to link gut microbial ecology to metabolic health. This is achieved using NMR-based metabolic profiling approaches combined to multivariate statistics. Applications include metabolic monitoring of diet intervention, exploration of the impact of gut microbiota on type II diabetes and metabolic syndrome, investigation of drug-bug interactions and development of new diagnostic tools for various intestinal diseases. Responsibilities: • Examinations Officer • Module convenor of FB3 PFB RP (Research Project) • Athena Swan Co-ordinator • CAF NMR Platform Manager Research groups / Centres: • ICMR • Centre for Food Security • Food Microbial Sciences Unit (FMSU)
Research Interest
My research focuses on the host-gut microbial metabolic interactions in order to link gut microbial ecology to metabolic health. This is achieved using NMR-based metabolic profiling approaches combined to multivariate statistics. Applications include metabolic monitoring of diet intervention, exploration of the impact of gut microbiota on type II diabetes and metabolic syndrome, investigation of drug-bug interactions and development of new diagnostic tools for various intestinal diseases.
Publications
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Matysik, S., Le Roy, C. I., Liebisch, G., and Claus, S. P. (2016) "Metabolomics of fecal samples: a practical consideration" Trends in Food Science Technology, Trends in Food Science and Technology, 57. pp. 244-255. ISSN 0924-2244 doi: 10.1016/j.tifs.2016.05.011
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Claus, S., (2017) "Inulin prebiotic: is it all about bifidobacteria?" Gut. ISSN 1468-3288 doi: 10.1136/gutjnl-2017-313800
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Le Roy, C. I., Passey, J. L., Woodward, M. J., La Ragione, R. M., and Claus, S. P. (2017) "Metabonomics-based analysis of Brachyspira pilosicoli's response to tiamulin reveals metabolic activity despite significant growth inhibition" Anaerobe, 45. pp. 71-77. ISSN 1075-9964 doi: 10.1016/j.anaerobe.2017.03.018