Daniel Hampshire

Biography

I joined the University of Sheffield in 2006 having previously worked and undertaken my PhD at the University of Leeds. I currently work with Prof. Anne Goodeve and Prof. Ian Peake on an National Institutes of Health (NIH) funded Program Project Grant (PPG

Research Interest

My field of interest is based on the application of molecular genetics to the investigation of cardiovascular disorders. Currently, my research is focused on investigating the plasma glycoprotein von Willebrand factor (VWF); specifically identifying factors which may contribute to the wide variation in VWF plasma levels observed in the general population, including the transcriptional regulation of the VWF gene and other genetic modifiers. I also have an interest in the associated bleeding disorder von Willebrand disease (VWD); specifically identifying further mechanisms involved in the pathogenesis of this disorder.