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John Zajicek

Chair in Medicine
Medicine
University of St Andrews
United Kingdom

Biography

Professor John Zajicek trained in Medicine at Cambridge and St Mary’s Hospital in London. He completed a PhD in cell biology in Cambridge, moved to Plymouth in 1995 as a Consultant Neurologist, and took up the Chair of Clinical Neuroscience at Plymouth University. In Plymouth he was Director of the Peninsula Clinical Trials Unit, and Chair of the UK NIHR Nervous System Disorders Specialty Group. He has recently moved to the University of St Andrews, where he is Professor of Medicine. Zajicek has served on the UK MRC Neuroscience and Mental Health Board and the MRC Methodology Panel. He is particularly interested in the way we do trials for neurodegenerative diseases, has been Chief Investigator in several large multicentre randomized controlled trials, including the investigation of cannabinoid use to slow neurodegeneration.

Research Interest

His research interest includes cannabinoids, multiple sclerosis and the methodology of clinical trials in neurodegeneration, including Alzheimer’s and Parkinson’s diseases.

Publications

  • McGhee, DJM, Ritchie, CW, Zajicek, JP & Counsell, CE 2016, 'A review of clinical trial designs used to detect a disease-modifying effect of drug therapy in Alzheimer’s disease and Parkinson’s disease' BMC Neurology, vol 16, 92, pp. 1-13. DOI: 10.1186/s12883-016-0606-3

  • Gunn, H, Andrade, J, Paul, L, Miller, L, Creanor, S, Green, C, Marsden, J, Ewings, P, Berrow, M, Vickery, J, Barton, A, Marshall, B, Zajicek, J & Freeman, JA 2017, 'Balance Right in Multiple Sclerosis (BRiMS): a guided self-management programme to reduce falls and improve quality of life, balance and mobility in people with secondary progressive multiple sclerosis: a protocol for a feasibility randomised controlled trial' Pilot and Feasibility Studies, vol 4, 26. DOI: 10.1186/s40814-017-0168-1

  • Cruz, PMR, Matthews, L, Boggild, M, Cavey, A, Constantinescu, CS, Evangelou, N, Giovannoni, G, Gray, O, Hawkins, S, Nicholas, R, Oppenheimer, M, Robertson, N, Zajicek, J, Rothwell, PM & Palace, J 2016, 'Time-and region-specific season of birth effects in multiple sclerosis in the United Kingdom' JAMA Neurology, vol 73, no. 8, pp. 954-960. DOI: 10.1001/jamaneurol.2016.1463

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