Li Wu
Professor
Department of Microbial Infection and Immunity
Food Animal Health Research Program, OARDC
United States Minor Outlying Islands
Biography
Li Wu had done his MS from Lanzhou Institute of Biological Products, China (1994-1997). Li Wu completed his PhD from Shanghai Medical College, Fudan University, China (1997-2000) and Postdoctoral Training from National Cancer Institute, NIH (2000-2005). At present he is Professor at The Ohio State University.
Research Interest
Molecular and cellular mechanisms of HIV replication and pathogenesis. HIV interactions with host factors Molecular mechanisms of cutaneous T-cell lymphoma
Publications
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St. Gelais C, Kim SH, Ding L, Yount J, Ivanov D, Spearman P, Wu L. A putative cyclin-binding motif in human SAMHD1 contributes to protein phosphorylation, localization and stability. J. Biol. Chem. 2016; 291(51): 26332–26342.
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Li C, Wang HB, Kuang WD, Ren XX, Song ST, Zhu HZ, Li Q, Xu LR, Guo HJ, Wu L*, and Wang J-H*. Naf1 regulates HIV-1 latency by suppressing viral promoter-driven gene expression in primary CD4+ T cells. J. Virol. 2017; 91 (1) e01830-16. ePub on 10/19/2016 * Co-corresponding authors
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Kohnken R, Kodigepalli KM, Mishra A, Porcu P, and Wu L. MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells of Sèzary syndrome patients. Leukemia Research. 2017; 52:58-66. ePub on 11/17/16
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Kodigepalli KM, Li M, Liu S-L, and Wu L. Exogenous expression of SAMHD1 inhibits proliferation and induces apoptosis in cutaneous T-cell lymphoma-derived HuT78 cells. Cell Cycle. 2017; 16(2):179-188. ePub on 12/9/16
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Duchon AA, St-Gelais C, Titkemeier N, Hatterschide J, Wu L, Musier-Forsyth K. HIV-1 exploits dynamic multi-aminoacyl-tRNA synthetase complex to enhance viral replication. J Virol. 2017 Aug 16. pii: JVI.01240-17. doi: 10.1128/JVI.01240-17. [Epub ahead of print]
