Maria C. Nagan
Professor
Chemistry
Adelphi University
United States of America
Biography
Maria C. Nagan completed Ph.D. Chemistry, University of Minnesota-Twin Cities (2001) B.A. Chemistry, Grinnell College (1997).2013 McNair Mentor Hall of Fame 2011 Sigma Xi, Kirksville Chapter - Researcher of the Year 2010 Walker and Doris Allen Fellowship for Faculty Excellence.
Research Interest
General: Computational studies examining thermodynamics of RNA structure and protein recognition of RNA Current Projects The role of water in RNA structure and recognition: We are employing explicit water molecular dynamics simulations to understand the role of water in RNA structure and recognition by other biomolecules in HIV and leukemia. The role of modified bases in RNA structure and recognition: We employ a variety of computational and experimental techniques to understand how naturally occurring modified bases change RNA structure and recognition.
Publications
-
Hati, S.; Ziervogel, B.; SternJohn, J.; Wong, F.-C.; Nagan, M.C.; Rosen, A.E.; Siliciano, P.G.; Chihade, J.W. and Musier-Forsyth, K. (2006), Pre-transfer Editing by Class II Prolyl-tRNA Synthetase: Role of Aminoacylation Active Site in "Selective Release" of Noncognate Amino Acids. J. Biol. Chem., 281, 27862-27872.
-
Michael, L.A.; Chenault, J.A.; Miller III, B.R.; Knolhoff, A.M. and Nagan, M.C. (2009), Water, Shape-Recognition, Salt Bridges and Pi-Cation Interactions Differentiate Peptide Recognition of the HIV Rev-Responsive Element. J. Mol. Biol., 392, 774-786.
-
Witts, R.N.; Hopson, E.C.; Koballa, D.E.; Van Boening, T.A.; Hopkins, N.H.; Patterson, E.V. and Nagan, M.C. (2013), Backbone-Base Interactions Critical to Quantum Stabilization of Transfer RNA Anticodon Structure. J. Phys. Chem. B, 117, 7489-7497.
