Richard E. Dearborn

Biography

 Dearborn Jr., R.E., Dai, Y., Reed, B., Gray, J. and Kunes, S. (2006). Reph, a regulator of Eph receptor expression and axonal topography in the Drosophila optic lobe. J. Neurosci. (submitted). Dearborn Jr., R.E. and Kunes, S. (2004). An axonal scaffold induced by retinal axons directs glia to destinations in the Drosophila optic lobe. Development. 131:2291-2303. Dearborn Jr., R.E., Qi, H., Kunes, S., and Dai, Y. (2002). Eph receptor tyrosine kinase-mediated formation of a topographic map in the development of the Drosophila visual system. J. Neurosci. 22:1338-1349. Dearborn Jr., R.E., Szaro, B.G. and Lnenicka, G.A. (1999). Cloning and characterization of AASPs: novel axon-associated SH3 binding-like proteins. J. Neurobiol. 38:581-594. Dearborn Jr., R.E., Szaro, B.G. and Lnenicka, G.A. (1998). Microinjection of mRNA encoding rat synapsin Ia alters synaptic physiology in identified motoneurons of the crayfish, Procambarus clarkii. J. Neurobiol. 37:224-236.

Research Interest

 My research focuses on brain development in the fruitfly, Drosophila, specifically the molecular characterization of Eph receptor signaling, which regulates axon guidance, vascular growth and tumorigenesis. Additional studies involve the elucidation of vitamin D3 up-regulated protein 1 (VDUP1) tumor suppressor regulation and function during brain development.