Jim Drake
Professor
Department of Immunology and Microbial Disease
Albany Medical College
United States of America
Biography
Dr. Jim Drake is currently working as a Professor in the Department of Department of Immunology and Microbial Disease, Albany Medical College , USA. His research interests includes Cell Biology and Molecular Mechanisms of Antigen Processing / Presentation, MHC Class II Conformers, B Cell Receptor Mediated Antigen Processing/Presentation, Macrophage Activation. He is serving as an editorial member and reviewer of several international reputed journals. Dr. Jim Drake is the member of many international affiliations. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to Cell Biology and Molecular Mechanisms of Antigen Processing / Presentation, MHC Class II Conformers, B Cell Receptor Mediated Antigen Processing/Presentation, Macrophage Activation.
Research Interest
Cell Biology and Molecular Mechanisms of Antigen Processing / Presentation, MHC Class II Conformers, B Cell Receptor Mediated Antigen Processing/Presentation, Macrophage Activation
Publications
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Busman-Sahay K, Drake L, Sitaram A, Marks M, Drake JR. Cis and trans regulatory mechanisms control AP2-mediated B cell receptor endocytosis via select tyrosine-based motifs. PLoS One. 2013;8(1):e54938. doi: 10.1371/journal.pone.0054938. PubMed PMID: 23372794; PubMed Central PMCID: PMC3553015.
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Franchini AM, Hunt D, Melendez JA, Drake JR. FcγR-driven release of IL-6 by macrophages requires NOX2-dependent production of reactive oxygen species. J Biol Chem. 2013 Aug 30;288(35):25098-108. doi: 10.1074/jbc.M113.474106. PubMed PMID: 23857584; PubMed Central PMCID: PMC3757174.
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Barroso M, Tucker H, Drake L, Nichol K, Drake JR. Antigen-B Cell Receptor Complexes Associate with Intracellular major histocompatibility complex (MHC) Class II Molecules. J Biol Chem. 2015 Nov 6;290(45):27101-12. doi: 10.1074/jbc.M115.649582. PubMed PMID: 26400081; PubMed Central PMCID: PMC4646406.
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Harton J, Jin L, Hahn A, Drake J. Immunological Functions of the Membrane Proximal Region of MHC Class II Molecules. F1000Res. 2016 Mar 17;5. pii: F1000 Faculty Rev-368. doi: 10.12688/f1000research.7610.1. Review. PubMed PMID: 27006762; PubMed Central PMCID: PMC4798158.
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Drake LA, Drake JR. A triad of molecular regions contribute to the formation of two distinct MHC class II conformers. Mol Immunol. 2016 Jun;74:59-70. doi: 10.1016/j.molimm.2016.04.010. PubMed PMID: 27148821; PubMed Central PMCID: PMC4899207.
