Emmanuel S. Burgos, Ph.d.
Research Assistant Professor
Biochemistry
Albert Einstein Medical College
United States of America
Biography
Dr. Emmanuel S. Burgos, Ph.D. is currently working as a Research Assistant Professor in the Department of Biochemistry, Albert Einstein College of Medicine , United States of America. His research interests includes Nicotinamide recycling and targeted inhibition of NAMPT for the development of novel therapeutics. Chemoenzymatic synthesis of co-factors and HTS platforms to identify selective methyltransferases' inhibitors. He is serving as an editorial member and reviewer of several international reputed journals. Dr. Emmanuel S. Burgos, Ph.D. is the member of many international affiliations. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to Nicotinamide recycling and targeted inhibition of NAMPT for the development of novel therapeutics. Chemoenzymatic synthesis of co-factors and HTS platforms to identify selective methyltransferases' inhibitors.
Research Interest
Nicotinamide recycling and targeted inhibition of NAMPT for the development of novel therapeutics. Chemoenzymatic synthesis of co-factors and HTS platforms to identify selective methyltransferases' inhibitors
Publications
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Keisha Thomas, Scott A. Cameron, Steven C. Almo, Emmanuel S. Burgos, Shivali A. Gulab, and Vern L. Schramm. 2015. “Active site and remote contributions to catalysis in methylthioadenosine nucleosidases.†Biochemistry, 54(15):2520-29 PMID: 25806409 doi: 10.1021/bi501487w
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Emmanuel S. Burgos, Carola Wilczek, Takashi Onikubo, Jeffrey B. Bonanno, Janina Jansong, Ulf Reimer, and David Shechter. 2015. “Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.†J. Biol. Chem., 290(15):9674-89. PMID: 25713080 doi: 10.1074/jbc.M115.636894
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Emmanuel S. Burgos, Ryan O. Walters, Derek M. Huffman, and David Shechter. 2017. “A simplified characterization of S-adenosyl-L-methionine-consuming enzymes with 1-Step EZ-MTase: a universal and straightforward coupled-assay for in vitro and in vivo setting.†Chem. Sci., 8: 6601-12. doi: 10.1039/C7SC02830J
