Andrew Jon Holland
Molecular Biology and Genetics
United States of America
Dr. Andrew J. Holland is an assistant professor of molecular biology and genetics at the Johns Hopkins University School of Medicine and holds a secondary appointment in Oncology. Dr. Holland's research focuses on the molecular mechanisms that control accurate chromosome distribution and the role of cell division errors in human health and disease. Dr. Holland received his undergraduate degree from the University of Cambridge, UK. He earned both his Ph.D. and Masters in Research at the University of Manchester, UK. He completed a postdoctoral fellowship at the Ludwig Institute for Cancer Research at the University of California, San Diego. Dr. Holland joined the Hopkins faculty in 2013.
The Holland lab is investigating in the molecular mechanisms that control accurate chromosome distribution and the role that mitotic errors play in human health and disease. Our work utilizes a combination of chemical biology, biochemistry, cell biology and genetically engineered mice to study pathways involved in mitosis and their effect on cell and organism physiology. A major focus of the group is to develop cell and animal-based models to study the role of cell division defects in genome instability and tumorigenesis.