Peter P. Lee
Professor
Immunotherapy
Beckman Research Institute
United States of America
Biography
Dr. Lee seeks to utilize immunotherapy as a less toxic approach to treating patients diagnosed with breast and other cancers. While many researchers focus on attacking the cancer cell itself, Dr. Lee aims to target the cancer cell as well as its ‘co-conspirators’ - support cells within the tissue stroma and tumor microenvironment. In order to survive, cancer cells recruit and manipulate these support cells, and as a result, a patient’s immune system is destroyed. Right now, Dr. Lee is studying these ‘co-conspirator’ cells to broaden his understanding of their interactions. By gaining a better understanding of the ways these co-conspirators help feed cancer cells, he may be able to develop therapeutics that target both malignant cells and their supporting cells - thereby, restoring and enhancing the immune function in patients with breast cancer.
Research Interest
Cancer and Immunity, Breast Cancer, Immunotherapy
Publications
-
Wang L, Miyahira AK, Simons DL, Lu X, Chang AY, Wang C, Suni MA, Maino VC, Dirbas FM, Yim J, Waisman J. IL6 Signaling in Peripheral Blood T Cells Predicts Clinical Outcome in Breast Cancer. Cancer research. 2017 Mar 1;77(5):1119-26.