Prabha Ibrahim

Biography

Prabha Ibrahim, Ph. D has worked in biopharmaceutical/pharma (Amgen, CV Therapeutics, Plexxikon, Afferent Pharmaceuticals, Merck) industry for more than 24 years and has held leadership roles in drug discovery and development in multiple therapeutic areas with a track record of identifying NCEs and advancing them through pre-clinical and clinical development. Her record of success and scientific achievements includes contributions to the nomination of multiple development candidates and filing of 16 INDs with one approved drug (Zelboraf) and two compounds at Ph3 (Pexidartinib) or Ph3 ready (MK-7264/AF-219). She was instrumental in the discovery and development of Zelboraf, first in class BRAF inhibitor approved in 2011 for metastatic melanoma and late phase development of Pexidartinib (first-in-class CSF-1R inhibitor) and AF-219 (first-in-class P2X3 receptor antagonist). Prabha was a Chief Technology Officer of Afferent Pharmaceuticals, Inc. from November 2015 and continued her responsibility with Merck, after acquisition, till March 2017. Prior to Afferent/Merck she held multiple positions at Plexxikon for 14 years with the last one being the Senior Vice President of Chemistry and Nonclinical Development. She led multidisciplinary teams and held multiple project and program leadership roles. Prior to Plexxikon, Prabha was a Senior Research Scientist and Group Leader at CV Therapeutics, where she was a project co-leader for cell cycle project and a lead chemist for the second generation Renexa program. She started her career as medicinal chemist at Amgen, where she played an integral role in small molecule drug discovery in inflammation. Dr. Ibrahim earned her Ph.D. at the University of Victoria, Canada, and was a Welch Foundation Fellow at Rice University, Houston. She received her M. Sc. Degree from The American College, Madurai, India, and her B.Sc. degree from RDM College, Sivaganga, India. Prabha Ibrahim, Ph. D has worked in biopharmaceutical/pharma (Amgen, CV Therapeutics, Plexxikon, Afferent Pharmaceuticals, Merck) industry for more than 24 years and has held leadership roles in drug discovery and development in multiple therapeutic areas with a track record of identifying NCEs and advancing them through pre-clinical and clinical development. Her record of success and scientific achievements includes contributions to the nomination of multiple development candidates and filing of 16 INDs with one approved drug (Zelboraf) and two compounds at Ph3 (Pexidartinib) or Ph3 ready (MK-7264/AF-219). She was instrumental in the discovery and development of Zelboraf, first in class BRAF inhibitor approved in 2011 for metastatic melanoma and late phase development of Pexidartinib (first-in-class CSF-1R inhibitor) and AF-219 (first-in-class P2X3 receptor antagonist). Prabha was a Chief Technology Officer of Afferent Pharmaceuticals, Inc. from November 2015 and continued her responsibility with Merck, after acquisition, till March 2017. Prior to Afferent/Merck she held multiple positions at Plexxikon for 14 years with the last one being the Senior Vice President of Chemistry and Nonclinical Development. She led multidisciplinary teams and held multiple project and program leadership roles. Prior to Plexxikon, Prabha was a Senior Research Scientist and Group Leader at CV Therapeutics, where she was a project co-leader for cell cycle project and a lead chemist for the second generation Renexa program. She started her career as medicinal chemist at Amgen, where she played an integral role in small molecule drug discovery in inflammation. Dr. Ibrahim earned her Ph.D. at the University of Victoria, Canada, and was a Welch Foundation Fellow at Rice University, Houston. She received her M. Sc. Degree from The American College, Madurai, India, and her B.Sc. degree from RDM College, Sivaganga, India.

Research Interest

Buisness