Cardiology Experts

Thomas M. Michel

Brigham & Womens Hospital
United States of America


Dr. Thomas M. Michel is a cardiovascular medicine specialist at Brigham and Women’s Hospital (BWH). In addition, he is a professor of medicine (Biochemistry) at Harvard Medical School (HMS) and the associate director of the Harvard/Massachusetts Institute of Technology MD-PhD Program.   After graduating from Harvard College, he received his MD and PhD degrees from Duke University School of Medicine. He completed an internal medicine residency, a clinical cardiology fellowship and a genetics research fellowship at BWH. He is board certified in internal medicine and cardiovascular disease.   Dr. Michel’s clinical interests include general cardiology and ischemic heart disease. The author of over 160 peer-reviewed publications, Dr. Michel’s research uses biochemical and cell biological approaches to understand signal transduction pathways in the cardiovascular system. His laboratory has studied endothelial nitric oxide synthase (eNOS), a signaling enzyme involved in the control of vascular tone, myocardial contractibility and platelet aggregation. An active educator, he served as the dean for education at Harvard Medical School. For the past two decades, the National Institutes of Health has provided continuous funding for his research endeavors.

Research Interest

My lab uses biochemical and cell biological approaches to explore signal transduction pathways in the cells and tissues of the cardiovascular system. We are particularly focused on studying the roles of reactive oxygen species and of nitric oxide synthases in endothelial cells and cardiac myocytes in cardiovascular disease states, including diabetes and atherosclerosis.

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