Karla Kirkegaard
PROFESSOR
MICROBIOLOGY AND IMMUNOLOGY
Canary Center at Stanford
United States of America
Biography
She is a Professor of Genetics,Microbiology & Immunology.She is a Faculty Fellow of Stanford ChEM-H. She is a Chair of Stanford University School of Medicine - Microbiology & Immunology (2006 - 2010).She is interested in many subcellular viruses and parasites, RNA, not DNA, is the carrier of genetic information. This has several interesting consequences for the genetics and biology of the virus. Poliovirus serves as a model to increase our understanding of positive-strand RNA viruses for which no vaccine is available and which remain a significant health hazard
Research Interest
How does the biochemistry of RNA-dependent RNA polymerases affect the biology of RNA viruses?
Publications
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Bird SW, Kirkegaard K. Escape of non-enveloped virus from intact cells. Virology. 2015 May 31;479:444-9.
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Bird SW, Kirkegaard K. Escape of non-enveloped virus from intact cells. Virology. 2015 May 31;479:444-9.
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Neufeldt CJ, Joyce MA, Van Buuren N, Levin A, Kirkegaard K, Gale Jr M, Tyrrell DL, Wozniak RW. The hepatitis C virus-induced membranous web and associated nuclear transport machinery limit access of pattern recognition receptors to viral replication sites. PLoS pathogens. 2016 Feb 10;12(2):e1005428.