William Weis
PROFESSOR
MOLECULAR AND CELLULAR PHYSIOLOGY
Canary Center at Stanford
United States of America
Biography
He is a Professor of Structural Biology, Photon Science Directorate, Molecular & Cellular Physiology.He is a Member of Bio-X, Stanford Cancer Institute.He is Faculty Fellow of Stanford ChEM-H.He is Director of Graduate Program in Biophysics (1999 - 2008),Chair of Department of Photon Science (2013 - 2016), Department of Structural Biology (2014 - Present).He has done Ph.D. from Harvard University, Biochemistry (1987)
Research Interest
The Wnt signaling pathway controls cell fate determination during embryogenesis and in the normal renewal of tissues in the adult. beta-catenin is the central component of this pathway
Publications
-
Feinberg H, Rambaruth ND, Jégouzo SA, Jacobsen KM, Djurhuus R, Poulsen TB, Weis WI, Taylor ME, Drickamer K. Binding sites for acylated trehalose analogs of glycolipid ligands on an extended carbohydrate recognition domain of the macrophage receptor Mincle. Journal of Biological Chemistry. 2016 Sep 30;291(40):21222-33.
-
Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Zhou Q, Zhao M, Brewster AS, Michels-Clark T, Holton JM, Sauter NK, Weis WI, Brunger AT. Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1/SNARE complex. Elife. 2016 Oct 12;5:e18740.
-
Kang H, Bang I, Jin KS, Lee B, Lee J, Shao X, Heier JA, Kwiatkowski AV, Nelson WJ, Hardin J, Weis WI. Structural and functional characterization of Caenorhabditis elegans α-catenin reveals constitutive binding to β-catenin and F-actin. Journal of Biological Chemistry. 2017 Apr 28;292(17):7077-86.
