Cedars Sinai Medical Center
United States of America
Cedars-Sinai Affiliations Department of Biomedical Sciences Awards & Activities Editorial Board: The Journal of Rare Disorders, Current Travel Award, International Society for Stem Cell Research, 2012 International Society for Stem Cell Research, 2010 Wisconsin Entrepreneurial Bootcamp Certificate, University of Washington School of Business, 2009 Society for Neuroscience, 2007 Harry Karavolas Graduate Student Scholarship, 2002
The research of Dhruv Sareen, PhD, focuses on molecular pathogenesis underlying neuro-developmental and -degenerative diseases, as well as understanding the molecular basis of signals that converge in the brain to impact energy metabolism and homeostasis in obesity. His research employs human induced pluripotent stem cell (iPSC)-based disease-in-a-dish models to understand the neurobiology of spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS), neurofibromatosis type 1 (NF1), and obesity. Bio-engineer human stem cell based ex vivo organ models. Sareen developed screening assays to test direct molecular therapeutics by high-content imaging in the iPSC-based cellular models.