Gadi Pelled

Biography

Education Undergraduate: Hebrew University of Jerusalem, 1992 Medical School: Hebrew University of Jerusalem, 1995 Doctorate: Hebrew University of Jerusalem, 2007 Cedars-Sinai Affiliations Biomedical Imaging Research Institute Department of Biomedical Sciences Department of Surgery Regenerative Medicine Institute (Board of Governors Regenerative Medicine Institute) Awards & Activities Member of Editorial Board: Journal of Regenerative Medicine and Tissue Engineering, 2012 Travel Award, The Institute of Molecular Imaging Sciences of the Academy of Molecular Imaging, World Molecular Imaging Congress, 2009 The Harvey M. Kruger Family Center For Nanoscience and Nanotechnology Prize, Hebrew University of Jerusalem, 2005 Finalist, New Investigator Research Award, Orthopedic Research Society, 2004 Short-term Research Grant, Minerva Foundation, 2003 Travel Award, American Society of Gene Therapy, 2003 The Isaac Kaye Innovations Award, Hebrew University of Jerusalem, 2002 The Golda Meir Fellow for Excellence, Hebrew University of Jerusalem, 2000 Rector's Scholarship for Excellent Graduate Students, Hebrew University of Jerusalem, 2000 Biomedical Research Training Scholarship, Israel Ministry of Health, 1999

Research Interest

Novel therapeutic platforms based on biological therapies are required to overcome extensive skeletal tissue loss or degeneration and replace the currently used synthetic prostheses. Complex clinical challenges such as intervertebral disc degeneration, osteoporotic vertebral fractures, tendon and ligament injuries, nonunion fractures and osteoarthritis pose a great challenge to health systems and to clinicians. Gadi Pelled, PhD, has been investigating the use of adult mesenchymal stem cells (MSCs) for skeletal tissue regeneration. His studies have shown that MSCs were able to regenerate skeletal tissues such as bone and tendon. Moreover, Pelled has shown, using state-of-the-art nanotechnological tools, that engineered bone generated by MSCs has chemical, topographical and nanomechanical properties similar to those of natural mature bone. State-of-the-art technologies are needed to promote tissue regeneration and monitor the effect of stem cell implantation. Pelled has used dynamic culture systems in his studies to investigate the feasibility of growing bone tissue in the lab. In addition, he has developed a novel imaging-based method to analyze tissue mechanics in vivo.