John Barnard
Associate Staff
Pathobiology
Cleveland Clinic Lerner Research Institute
United States of America
Biography
Our laboratory studies nitric oxide (NO) biosynthesis in mammals. NO is made by an enzyme named NO synthase, and is involved in many aspects of cell function and disease, including signal transduction in the brain, control of blood pressure and heart rate, gastric motility, oxygen delivery, immunologic destruction of tumor cells and microbes, infertility, impotence, and stroke.
Research Interest
Design and analysis of genomic and genetic studies; design and analysis of transcriptomic and integrated-omic studies; data mining