Mitchell Alan Olman
Associate Staff
Pathobiology
Cleveland Clinic Lerner Research Institute
United States of America
Biography
Our research is focused on the pathogenesis on the fatal and untreatable disorder of idiopathic pulmonary fibrosis. The general approach we adopt is to investigate pulmonary fibrosis at the molecular level, in cells and animal models, and to validate the newly-discovered pathways using patient samples.
Research Interest
fibrosis; pulmonary; fibroblast; TRP ion channel; coagulation; myofibroblast
Publications
-
Q Ding, C Gladson, H Wu, H Haysaka and MA Olman. FAK-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner. J Biol Chem 2008; 283:26839-49
-
K White, Q Ding, B Moore, M Peters-Golden, L Ware, M Matthay and M.A. Olman.PGE2 mediates IL-1β-related fibroblast mitogenic effects in acute lung injury through differential utilization of prostanoid receptors. J Immunol 180 (1): 637-646; 2008
