Qing Yi
Chair
Cancer Biology
Cleveland Clinic Lerner Research Institute
United States of America
Biography
Yi has been working on tumor immunology and immunotherapy in multiple myeloma (MM) for 20 years. We were first to demonstrate the existence of idiotype-specific T cells in patients with MM and related disorders and that idiotype-specific cytotoxic T cells could lyse autologous primary myeloma cells.
Research Interest
Antitumor immune response; C-reactive protein; Cancer; Drug resistance; Idiotype; Immunotherapy; Mantle cell lymphoma; Monoclonal antibodies; Multiple myeloma; T cells; Tumor microenvironment; Vaccines
Publications
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Lu Y (2012) Th9 cells promote antitumor immune responses in vivo. J Clin Invest 122:4160-4171.
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Qian J, (2012) Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma. Blood 119:161-169.
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Zheng Y(2013) PSGL-1/selectin and ICAM-1/CD18 interactions are involved in macrophage-induced drug resistance in myeloma. Leukemia 27:702--710.
