Tatiana V Byzova
Staff
Molecular Cardiology
Cleveland Clinic Lerner Research Institute
United States of America
Biography
The major objective of my research program is to fully integrate the mechanistic studies performed at the molecular and cellular levels with complex in vivo models of human diseases to yield a complete understanding of fundamental problems in physiology and pathophysiology.
Research Interest
Angiogenesis; Endothelial Cells; Integrins; Extracellular Matrix; Cell Adhesion; Tumor Progression; Vascular Biology; Signal Transduction in Endothelium and Platelets; Oxidative Stress and Vasculature; Toll-like Receptors in Angiogenesis.
Publications
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Kim YW, Yakubenko VP, West XZ, Gugiu GB, Renganathan K, Biswas S, Gao D, Crabb JW, Salomon RG, Podrez EA, Byzova TV. "Receptor-Mediated Mechanism Controlling Tissue Levels of Bioactive Lipid Oxidation Products." Circulation Research (2015): 117(4):321-32.
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Kerr BA, West XZ, Kim YW, Zhao Y, Tischenko M, Cull RM, Phares TW, Peng XD, Bernier-Latmani J, Petrova TV, Adams RH, Hay N, Naga Prasad SV, Byzova TV. "Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium." Nature Communications (2016): 7:10960.