Cory Abate-shen
Professor
Department of System Biology
Columbia University
United States of America
Biography
"Cory Abate-Shen is a professor in the Department of Urology and Department of Pathology and Cell Biology, the Michael and Stella Chernow Chair of Urological Oncology, and an associate director of the Herbert Irving Cancer Center. She is investigating the molecular mechanisms of homeobox genes in development and cancer. Her laboratory has provided groundbreaking insights on the molecular bases of how homeoproteins achieve target gene recognition in vivo. She has also developed mouse models of prostate cancer that have been widely used to investigate the molecular bases of prostate tumorigenesis and as preclinical models for intervention and therapy. She has been the recipient of several awards, including a Sinsheimer Scholar Award, an NSF Young Investigator Award, and the Women in Cell Biology Junior Award from the American Society for Cell Biology. She is currently the principal investigator on five federal grants including an NCI consortium grant on Mouse Models of Human Cancer. In addition, she has received funding from several other sources including the March of Dimes, the New Jersey Commission on Cancer Research and the Gustave and Louise Pfeiffer Research Foundation. She has recently been named an American Association of Cancer Research Professor. "
Research Interest
Cancer Systems Therapeutics
Publications
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Shen MM, Abate-Shen C(2010)Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev 24:1967-2000.
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Wang J, Kumar R, Biggs VJ, Lee H, Chen Y, et al. 2011) The Msx1 homeoprotein recruits Polycomb to the nuclear periphery during development. Dev Cell. 21:575-588