Tuuli Lappalainen
Assistant Professor
Department of System Biology
Columbia University
United States of America
Biography
"Tuuli Lappalainen is an Assistant Professor in the Department of Systems Biology at Columbia University and a Junior Investigator and Core Member at the New York Genome Center. Her research focuses on functional genetic variation in human populations and its contribution to traits and diseases. The work of her research group, physically located at New York Genome Center in lower Manhattan, links computational and population genomics to experimental molecular biology. While their individual projects may focus on specific diseases, the overall goal is to uncover general rules of the genomic sources of human variation. She also seeks to push the discoveries and methods from her research projects further towards clinical applications."
Research Interest
Biochemistry and Molecular Biophysics
Publications
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Lappalainen T , Sammeth M, Friedlander M, ‘t Hoen PAC, Rivas MA, et al.(2016) Transcriptome and genome sequencing uncovers human functional variation. Nature 501: 506-511.
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Lappalainen T, Montgomery SB, Nica AC, Dermitzakis ET (2011) Epistatic selection between coding and regulatory variation in human evolution and disease. Am J Hum Genet. 9;89):459-63
