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Yufeng Shen

Assistant Professorq
Department of Genetics and Development
Columbia University
United States of America

Biography

"Yufeng Shen is an assistant professor in the Columbia University Department of Systems Biology and Department of Biomedical Informatics. After completing his PhD in computational biology in 2007 at the Human Genome Sequencing Center at Baylor College of Medicine, he led the analysis of the first personal genome produced by next-generation sequencing (that of Dr. James D. Watson). In 2008 he joined Columbia University as a postdoctoral fellow, working in computational genomics and genetics of drug adverse reactions, and then joined the faculty in July 2011. Dr. Shen is interested in developing and applying computational methods to study human genetics and diseases. The research in his group is at the interface of biology, statistics, and computer science. Specifically, his group is working in four areas, including genome sequencing and assembly, mapping of disease genes, the role of the major histocompatibility complex (MHC) in autoimmunity, and pharmacogenomics.

Research Interest

Genomoics

Publications

  • Shen Y, Song R, Pe'er I. Coverage tradeoffs and power estimation in the design of whole-genome sequencing experiments for detecting association. Bioinformatics. 2011 Jul 15;27(14):1995-7.

  • Shen Y, Nicoletti P, Floratos A, Pirmohamed M, Molokhia M, Geppetti P, Benemei S, Giorni B, Schena D, Vultaggio A, Stern R, Daly MJ, John S, Nelson MR, Pe’er I. Genome-wide association study of serious blistering skin rash caused by drugs. Pharmacogenomics J.

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