Vice President of Translational Biology
United States of America
Mary Simcox serves as the Vice President of Translational Biology for Cue Biopharma. Before joining Cue, Dr. Simcox held various leadership positions at Tarveda Therapeutics, FORMA Therapeutics and Roche. Prior to Tarveda, she was Director of Biology at FORMA, where she oversaw the protein homeostasis target project portfolio. In this role, she led the discovery efforts to characterize novel pathway biology to discover and characterize potent and selective small molecule inhibitors to progress toward clinical development. Prior to FORMA, she held several leadership roles at Roche, where she led several small molecule and antibody projects into clinical development, worked to understand the mechanisms of resistance to Zelboraf® and Avastin®, led translational work on an anti-TWEAK antibody, and led discovery programs for the development of small molecule inhibitors of VEGFR2 and CDK2. Her undergraduate and doctoral work were completed at the University of California at Davis, where she earned a B.S. in Biochemistry and a Ph.D. in Nutrition
She led the discovery efforts to characterize novel pathway biology to discover and characterize potent and selective small molecule inhibitors to progress toward clinical development.