Bradley A Arrick
Associate Professor
Department of Medical Education
Dartmouth College
United States of America
Biography
Bradley A Arrick is currently working as Associate Professor of Medical Education, Dartmouth Medical College. He has authored and co-authored multiple pepeer-reviewed scientific papers and presented works at many national and International conferences.
Research Interest
One of the most versatile and potent of growth-regulatory proteins, TGF-β, is a major focus of Dr. Arrick's research. Particular attention is being directed at efforts to better understand the role of TGF-β in tumor formation and the malignant phenotype, using the model of breast cancer. A second focus of research in Dr. Arrick's lab is elucidation of the function(s) of the recently-discovered gene responsible for many cases of inherited breast cancer (called BRCA1).
Publications
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Kuhn JC, Siegel A, Poplack S, Arrick B. Chest wall recurrence of breast cancer detected by scintimammography. Clinical Nuclear Medicine 25:104-106, 2000.
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Archey W, Sweet MP, Alig G, and Arrick BA. Methylation of CpGs as a determinant of transcriptional activation at alternative promoters for transforming growth factor-beta3. Cancer Research, 59:2292-2296, 1999.
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Lu M, Conzen SD, Cole CN, and Arrick BA. Characterization of functional splice variants of BRC1 expressed in non-malignant and tumor-derived breast cells. Cancer Research 56:4578-4581, 1996.
