Benjamin Janto
Assistant Professor
Microbiology & Immunology
Drexel University College of Medicine
United States of America
Biography
Dr. Janto is an assistant professor in the Department of Microbiology & Immunology at Drexel University College of Medicine. PhD - Drexel University College of Medicine (2012)
Research Interest
He works towards the goal of developing alternative targeted treatment strategies to combat chronic bacterial biofilm disease based on two underlying principles: 1) manipulation of bacterial behavior as opposed to eradication; and 2) the specific targeting of virulent strains and the sparing of commensal strains of the same species. Our normal bacterial flora plays a key role in our health in ways that we are only beginning to appreciate. Furthermore, our current antibiotic treatments are failing due to increasing resistance and a reduction in discovery and development. Therefore we seek to shift the clinical paradigm of treatment of chronic bacterial diseases away from traditional broad-spectrum antibiotics towards alternative strategies including behavioral manipulation and/or more targeted approaches at the subspecies or strain-level.
Publications
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Ahmed A, Earl J, Retchless A, Hillier SL, Rabe LK, Cherpes TL, Powell E, Janto B, Eutsey R, Hiller NL, Boissy R. Comparative genomic analyses of seventeen clinical isolates of Gardnerella vaginalis provides evidence of multiple genetically isolated clades consistent with sub-speciation into genovars. Journal of bacteriology. 2012 May 18:JB-00056.
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Eutsey RA, Hiller NL, Earl JP, Janto BA, Dahlgren ME, Ahmed A, Powell E, Schultz MP, Gilsdorf JR, Zhang L, Smith A. Design and validation of a supragenome array for determination of the genomic content of Haemophilus influenzae isolates. BMC genomics. 2013 Jul 17;14(1):484.
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Janto BA, Hiller NL, Eutsey RA, Dahlgren ME, Earl JP, Powell E, Ahmed A, Hu FZ, Ehrlich GD. Development and validation of an Haemophilus influenzae supragenome hybridization (SGH) array for transcriptomic analyses. PloS one. 2014 Oct 7;9(10):e105493.
