Drexel University College of Medicine
United States of America
Dr. Orynbayeva is an assistant professor in the Department of Surgery at Drexel University College of Medicine.
Mitochondria pathophysiology focusing on tissue-specific bioenergetic signature of tumors types, development of anti-cancer therapies by targeting mitochondria energetic metabolism, and single cell-based array nanotechnologies for analysis of cellular metabolomics
“Metabolic and structural integrity of magnetic nanoparticle-loaded primary endothelial cells for targeted cell therapy” Z Orynbayeva, R Sensenig, B Polyak Nanomedicine - Future Medicine, 10(10), 1555-68 (2015)
“Knockout of cyclophilin D in Ppif-/- mice increases stability of brain mitochondria against Ca2+ stress” T Gainutdinov, JD Molkentin, D Siemen, M Ziemer, G Debska-Vielhaber, S Vielhaber, Z Gizatullina, Z Orynbayeva, FN Gellerich Archives of Biochemistry and Biophysics, 579, 40-6 (2015)
“Tumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondria” A Zhunussova, B Sen, L Friedman, S Tuleukhanov, AD Brooks, R Sensenig, Z Orynbayeva American Journal of Cancer Research, 5(5), 1665-79 (2015)