Fraser Fleming
Department Head
Department of Chemistry
Drexel University
United States of America
Biography
Fraser Fleming earned his BS (Hons.) at Massey University, New Zealand, in 1986 and a PhD under the direction of Edward Piers at the University of British Columbia, Canada, in 1990. After postdoctoral research with James D. White at Oregon State University he joined the faculty at Duquesne University, Pittsburgh, in 1992. In 2013 he took a temporary position as a program director at the National Science Foundation working in the Synthesis Program and the Catalysis Program. His research interests lie in stereochemistry and organometallics, particularly as applied to the reactions of nitriles and isonitriles
Research Interest
Rapidly constructing biologically relevant scaffolds as potential pharmaceutical leads, metalated nitriles as potent nucleophiles for hindered bond construction, metalated isocyanides as precursors to peptide mimics
Publications
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Arylthio-Metal Exchange of α-Arylthioalkanenitriles" Nath, D.; Skilbeck, M.; Coldham, I.; Fleming, F. F. Org. Lett. 2014, 16, 62−65.
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"Alkyl Sulfinates: Formal Nucleophiles for Synthesizing TosMIC Analogs" Montelongo, J. A. L.; Estevez, A. O.; Fleming, F. F. Eur. J. Org. Chem. 2015, 1602-1605
