Kara Spiller
Assistant Professor
School of Biomedical Engineering, Science & Health Systems
Drexel University
United States of America
Biography
"Kara received her bachelor's and master's degrees in biomedical engineering from Drexel University in 2007. She conducted her doctoral research in the design of semi-degradable hydrogels for the repair of articular cartilage in the Biomaterials and Drug Delivery Laboratory at Drexel and in the Shanghai Key Tissue Engineering Laboratory of Shanghai Jiao Tong University. After completing her PhD in 2010, when she received the award for Most Outstanding Doctoral Graduate: Most Promise to Enhance Drexel's Reputation, she conducted research in the design of scaffolds for bone tissue engineering as a Fulbright Fellow in the Biomaterials, Biodegradables, and Biomimetics (the 3Bs) Research Group at the University of Minho in Guimaraes, Portugal. She is currently conducting research in the design of immunomodularatory biomaterials, particularly for bone tissue engineering. Her research interests include cell-biomaterial interactionns, biomaterial design, and international engineering education. "
Research Interest
"Macrophage-biomaterial interactions, drug delivery systems, and chronic wound healing. "
Publications
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"Nassiri S, Zakeri I, Weingarten MS, Spiller KL. Relative Expression of Proinflammatory and Antiinflammatory Genes Reveals Differences between Healing and Nonhealing Human Chronic Diabetic Foot Ulcers. The Journal of investigative dermatology. 2015; 135(6):1700-3. PubMed [journal] PMID: 25647438"
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"Spiller KL, Freytes DO, Vunjak-Novakovic G. Macrophages modulate engineered human tissues for enhanced vascularization and healing. Annals of biomedical engineering. 2015; 43(3):616-27. NIHMSID: NIHMS636869 PubMed [journal] PMID: 25331098, PMCID: PMC4380684"
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"Spiller KL, Nassiri S, Witherel CE, Anfang RR, Ng J, et al. Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds. Biomaterials. 2015; 37:194-207. NIHMSID: NIHMS638428 PubMed [journal] PMID: 25453950, PMCID: PMC4312192"
