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Ming Xiao

Associate Professor 
School of Biomedical Engineering, Science & Health Systems
Drexel University
United States of America

Biography

Dr. Ming Xiao joined Drexel University in the School of Biomedical Engineering, Science and Health System in Summer 2012. Dr. Xiao received a PhD from the Baylor University in Biophysics. Dr. Xiao completed his Postdoctoral training at the University of Illinois, Urbana & Champaign, where he continued his studies in the molecular mechanism of muscle contraction. For the past decade, Dr. Xiao has been involved in nanogenomics, a field that aims to develop nanotechnologies in accelerating the genomic studies. More recently, Dr. Xiao was the director of advanced technology at Bionano Genomics, Inc, and one of the founding scientists of the company. Dr. Xiao's current research effort is split between technology development and biological applications. Technique development includes single molecule analysis of biomolecules (DNA, protein, RNA) under nanoplatform using advanced physical and chemical methods. One of such unique and innovative techniques, genome mapping, has been demonstrated in assisting the de novo assembly of sequencing reads from complex genomes, haplotype and structural variation analysis and comparative genomics.

Research Interest

Nanotechnology, single molecule detection, single molecule fluorescent imaging, genomics, genetics, genome mapping, DNA sequencing, DNA biochemistry, and biophysics.

Publications

  • Xiao, M., Wan, E., Chu, C.,Hsueh, W. C., Cao, Y.,Kwok, P. Y.(2009). Direct determination of haplotypes from single DNA molecules. Nature Methods 6(3):199-201

  • Baday, M., Hastie, A., Kudeki, D.E., Xiao, M., Selvin, P.R. (2012) Multi-color super-resolution DNA imaging for genetic analysis. Nano letters, 12 (7), 3861-3866

  • Lam, L.E., Hastie, A., Lin, C., Ehrlich, D., Das, S.K., Austin, M.D., Cao, H., Deshpande, P., Nagarajan, N., Xiao, M., Kwok, P.Y. (2012) Genome mapping for structural variation analysis and sequence assembly in nano-channel. Nature Biotechnology, 30 (8), 771-776.

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