Gowthami Morey Arepally
Associate Professor
Hematology
Duke University School of Medicine
United States of America
Biography
Gowthami M. Arepally, M.D. is an Associate Professor in the Division of Hematology at Duke University Medical Center and the Medical Director of Therapeutic Apheresis at Duke. Her clinical interests are in immune thrombocytopenias, thrombotic disorders, and applications of therapeutic apheresis for immunologic disorders. Dr. Arepally’s long-standing research program investigates immunoregulatory mechanisms in HIT. Current laboratory efforts focus on the role of complement activation in the immune pathogenesis of HIT, investigations of protamine/heparin antibodies and development of murine models for studies of the HIT immune response. Clinical projects include applications of therapeutic apheresis, including development of a multi-site network for investigations of thrombotic microangiopathy, studies of therapeutic plasma exchange for HIT and solid organ transplantation. Gowthami M. Arepally, M.D. is an Associate Professor in the Division of Hematology at Duke University Medical Center and the Medical Director of Therapeutic Apheresis at Duke. Her clinical interests are in immune thrombocytopenias, thrombotic disorders, and applications of therapeutic apheresis for immunologic disorders. Dr. Arepally’s long-standing research program investigates immunoregulatory mechanisms in HIT. Current laboratory efforts focus on the role of complement activation in the immune pathogenesis of HIT, investigations of protamine/heparin antibodies and development of murine models for studies of the HIT immune response. Clinical projects include applications of therapeutic apheresis, including development of a multi-site network for investigations of thrombotic microangiopathy, studies of therapeutic plasma exchange for HIT and solid organ transplantation.
Research Interest
Hematology
Publications
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Arepally, GM. "Heparin-induced thrombocytopenia." Blood 129, no. 21 (May 2017): 2864-2872. (Review)
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Fountain, EM, and Arepally, GM. "Etiology and complications of thrombocytopenia in hospitalized medical patients." Journal of thrombosis and thrombolysis 43, no. 4 (May 2017): 429-436.
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Abbes, S, Metjian, A, Gray, A, Martinu, T, Snyder, L, Chen, D-F, Ellis, M, Arepally, GM, and Onwuemene, O. "Human Leukocyte Antigen Sensitization in Solid Organ Transplantation: A Primer on Terminology, Testing, and Clinical Significance for the Apheresis Practitioner." Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 21, no. 5 (October 2017): 441-450. (Review)
