Pharmaceutical Sciences
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Pharmaceutical Sciences Experts

David Lapinsky

Associate Professor
School of Pharmacy
Duquesne University
United States of America

David Lapinsky

Biography

David Lapinsky is working as professor at School of Pharmacy, Duquesne University. His area of research include Target identification of hit compounds originating from phenotypic screening campaigns,Mechanism of action studies, confirmation of target engagement, or selectivity profiling (also known as Affinity-Based Protein Profiling (AfBPP)),Characterizing the interactions of small-molecules with drug targets, Determining binding sites within target proteins

Research Interest

Target identification of hit compounds originating from phenotypic screening campaigns, Mechanism of action studies, confirmation of target engagement, or selectivity profiling (also known as Affinity-Based Protein Profiling (AfBPP)), Characterizing the interactions of small-molecules with drug targets, Determining binding sites within target proteins

Publications

  • Recent developments and applications of clickable photoprobes in medicinal chemistry and chemical biology. Lapinsky, David J.; Johnson, Douglas S. Future Medicinal Chemistry (2015), 7(16), 2143-2171.

  • Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators. Gregory, Karen J.; Velagaleti, Ranganadh; Thal, David M.; Brady, Ryan M.; Christopoulos, Arthur; Conn, P. Jeffrey; Lapinsky, David J. ACS Chemical Biology (2016), 11(7), 1870-1879.

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