School of Pharmacy
United States of America
Kevin Tidgewell is working as professor at School of Pharmacy, Duquesne University. Tidgewell works in the fields of Medicinal and Natural Products Chemistry. His work focuses on the discovery of novel ligands from marine cyanobacteria for GPCR targets. Projects in the lab range from extraction, isolation and structure elucidation of novel leads to semi-synthetic medicinal chemistry lead optimization. The major focus of his work is on pain and addiction with the broader scope being GPCRs involved in regulating CNS processes and other complex disease states.
Medicinal and Natural Products Chemistry.
Harding, W.W.; Schmidt, M.D.; Tidgewell, K.; Kannan, P.; Holden, K.G.; Dersch, C.M.; Rothman, R.B.; Prisinzano, T.E. Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Selective Modification of the Furan Ring. Bio. Med. Chem. Letters. 2006 (16): 3170-3174.
Harding, W.W.; Schmidt, M.; Tidgewell, K.; Kannan, P.; Holden, K.G.; Gilmour, B.; Navarro, H.; Rothman, R.B.; Prisinzano, T.E. Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Semisynthesis of Salvinicins A and B and Other Chemical Transformations of Salvinorin A. J. Nat. Prod. 2006 (69): 107-112.