Donald Gerecke
Associate Professor
Toxicology
Environmental and Occupational Health Sciences Institute
United States of America
Biography
Dr Gerecke received his BS in Animal Science (1972) and MS in Entomology and Economic Zoology (1976) from Rutgers University. Upon graduation, Dr Gerecke worked over ten years as a research pesticide chemist, first at UniRoyal and then at Rhone-Poulenc. He next entered the Anatomy and Cellular Biology graduate program at Harvard University where he obtained his PhD in 1992. He spent the next five years as a research fellow and instructor at Harvard Medical School Department of Dermatology. Dr Gerecke is presently an Associate Professor in the Pharmacology & Toxicology Department at the Ernest Mario School of Pharmacy, Rutgers University, where he teaches in the PharmD, Graduate program in Toxicology, and undergraduate Arts and Sciences programs. His research program has been continuously funded by the NIH and the Department of Defense since 2001. He has trained 3 M.S. and Ph.D. students, mentored 23 Pharmacy students and is currently supervising 1 Ph.D. and 2 Pharm.D Honor students.
Research Interest
Toxicology
Publications
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Chang, YC, Wang, JD, Hahn, RA, Gordon, MK, Joseph, LB, Heck, DE, Heindel, ND, Young, SC, Sinko, PJ, Casillas, RP et al.. Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard. Toxicol. Appl. Pharmacol. 2014;280 (2):236-44. doi: 10.1016/j.taap.2014.07.016. PubMed PMID:25127551 PubMed Central PMC4254337
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DeSantis-Rodrigues, A, Chang, YC, Hahn, RA, Po, IP, Zhou, P, Lacey, CJ, Pillai, A, C Young, S, Flowers, RA 2nd, Gallo, MA et al.. ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure. Invest. Ophthalmol. Vis. Sci. 2016;57 (4):1687-98. doi: 10.1167/iovs.15-17269. PubMed PMID:27058125 PubMed Central PMC4829087
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Wohlman, IM, Composto, GM, Heck, DE, Heindel, ND, Lacey, CJ, Guillon, CD, Casillas, RP, Croutch, CR, Gerecke, DR, Laskin, DL et al.. Mustard vesicants alter expression of the endocannabinoid system in mouse skin. Toxicol. Appl. Pharmacol. 2016;303 :30-44. doi: 10.1016/j.taap.2016.04.014. PubMed PMID:27125198 PubMed Central PMC4947375
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Composto, GM, Laskin, JD, Laskin, DL, Gerecke, DR, Casillas, RP, Heindel, ND, Joseph, LB, Heck, DE. Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug. Exp. Mol. Pathol. 2016;100 (3):522-31. doi: 10.1016/j.yexmp.2016.05.008. PubMed PMID:27189522 PubMed Central PMC4947376
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Gordon, MK, DeSantis-Rodrigues, A, Hahn, R, Zhou, P, Chang, Y, Svoboda, KK, Gerecke, DR. The molecules in the corneal basement membrane zone affected by mustard exposure suggest potential therapies. Ann. N. Y. Acad. Sci. 2016;1378 (1):158-165. doi: 10.1111/nyas.13226. PubMed PMID:27737494 PubMed Central PMC5221489
