Howard Kipen
Interim Chair and Professor
Clinical Research and Occupational Medicine
Environmental and Occupational Health Sciences Institute
United States of America
Biography
Dr. Kipen’s research focuses on clinical and epidemiological studies of the health effects of ambient air pollution. He works closely with Rob Laumbach of the CROM division as well as Qingyu Meng of Exposure Science and Debra Laskin and Andrew Gow of Toxicology. They use both controlled exposure models with ozone, fresh aerosols, and diesel-enriched on-road exposures, primarily with drives on the New Jersey Turnpike. A new EPA study examines health benefits of portable air cleaners for reducing indoor air pollution levels. Biomarker outcomes presently emphasized are exhaled breath oxidative stress and invasive and noninvasive measures of vascular function.
Research Interest
Clinical Research, Occupational Medicine
Publications
-
Pettit, AP, Kipen, H, Laumbach, R, Ohman-Strickland, P, Kelly-McNeill, K, Cepeda, C, Fan, ZH, Amorosa, L, Lubitz, S, Schneider, S et al.. Disrupted Nitric Oxide Metabolism from Type II Diabetes and Acute Exposure to Particulate Air Pollution. PLoS ONE. 2015;10 (12):e0144250. doi: 10.1371/journal.pone.0144250. PubMed PMID:26656561 PubMed Central PMC4682772
-
Altemose, B, Robson, MG, Kipen, HM, Ohman Strickland, P, Meng, Q, Gong, J, Huang, W, Wang, G, Rich, DQ, Zhu, T et al.. Association of air pollution sources and aldehydes with biomarkers of blood coagulation, pulmonary inflammation, and systemic oxidative stress. J Expo Sci Environ Epidemiol. 2017;27 (3):244-250. doi: 10.1038/jes.2016.38. PubMed PMID:27436693
-
Patton, AP, Laumbach, R, Ohman-Strickland, P, Black, K, Alimokhtari, S, Lioy, P, Kipen, HM. Scripted drives: A robust protocol for generating exposures to traffic-related air pollution. Atmos Environ (1994). 2016;143 :290-299. doi: 10.1016/j.atmosenv.2016.08.038. PubMed PMID:27642251 PubMed Central PMC5019181
-
Sunil, VR, Vayas, KN, Fang, M, Zarbl, H, Massa, C, Gow, AJ, Cervelli, JA, Kipen, H, Laumbach, RJ, Lioy, PJ et al.. World Trade Center (WTC) dust exposure in mice is associated with inflammation, oxidative stress and epigenetic changes in the lung. Exp. Mol. Pathol. 2017;102 (1):50-58. doi: 10.1016/j.yexmp.2016.12.005. PubMed PMID:27986442 PubMed Central PMC5472054
-
Thurston, GD, Kipen, H, Annesi-Maesano, I, Balmes, J, Brook, RD, Cromar, K, De Matteis, S, Forastiere, F, Forsberg, B, Frampton, MW et al.. A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Eur. Respir. J. 2017;49 (1):. doi: 10.1183/13993003.00419-2016. PubMed PMID:28077473
