Jay A Tischfield
Professor I, Chief Executive Officer and Scientifi
Toxicology
Environmental and Occupational Health Sciences Institute
United States of America
Biography
Our primary research interests include studies of both somatically heritable and transient genetic changes in somatic cells that predispose to disease in humans. In addition, we are engaged in several large projects whose ultimate goal is the identification of genes that have major contributions to complex oligogenic disorders.
Research Interest
Toxicology
Publications
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Willsey, AJ, Fernandez, TV, Yu, D, King, RA, Dietrich, A, Xing, J, Sanders, SJ, Mandell, JD, Huang, AY, Richer, P et al.. De Novo Coding Variants Are Strongly Associated with Tourette Disorder. Neuron. 2017;94 (3):486-499.e9. doi: 10.1016/j.neuron.2017.04.024. PubMed PMID:28472652
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Abdulkadir, M, Londono, D, Gordon, D, Fernandez, TV, Brown, LW, Cheon, KA, Coffey, BJ, Elzerman, L, Fremer, C, Fründt, O et al.. Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. Eur Arch Psychiatry Clin Neurosci. 2017; :. doi: 10.1007/s00406-017-0808-8. PubMed PMID:28555406
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Andersen, AM, Pietrzak, RH, Kranzler, HR, Ma, L, Zhou, H, Liu, X, Kramer, J, Kuperman, S, Edenberg, HJ, Nurnberger, JI Jr et al.. Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence. JAMA Psychiatry. 2017; :. doi: 10.1001/jamapsychiatry.2017.2269. PubMed PMID:28813562
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Kuperman, S, Chan, G, Kramer, J, Wetherill, L, Acion, L, Edenberg, HJ, Foroud, TM, Nurnberger, J Jr, Agrawal, A, Anokhin, A et al.. A GABRA2 polymorphism improves a model for prediction of drinking initiation. Alcohol. 2017;63 :1-8. doi: 10.1016/j.alcohol.2017.03.003. PubMed PMID:28847377
