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Toxicology Experts

Tamara Minko

Distinguished Professor
Toxicology
Environmental and Occupational Health Sciences Institute
United States of America

Biography

Dr. Tamara Minko is a Professor II and Chair of the Department of Pharmaceutics at Rutgers, The State University of New Jersey. She is also a member of the Cancer Institute of New Jersey, Environmental and Occupational Health Sciences Institute. Her current research interests include drug delivery; biopharmaceutics; nanotechnology; molecular targeting; antisense oligonucleotides, siRNA and peptide delivery; mechanisms of multidrug resistance; intracellular fate and molecular mechanisms of action of anticancer drugs; bioimaging; macromolecular therapeutics; preclinical evaluation of new therapeutics; modulation of cell death mechanisms during hypoxia. Professor Minko is author and co-author of more than 400 publications (peer-reviewed papers, books and textbook chapters, conference proceedings, patents). Many of her papers are well cited and published in prestigious journals with high impact factors including PNAS, Nature Nanotechnology, Cancer Research, Clinical Cancer Research, Advanced Drug Delivery Review, Journal of Controlled Release, etc. Dr. Minko is a Fellow of the American Association of Pharmaceutical Scientists, elected member of the Board of Scientific Advisors of the Controlled Release Society, recipient of numerous awards, Editor of Pharmaceutical Research, member of editorial board of several scientific journals and a member of Study Sections at NIH, DOD, American Heart Association and other national and international review panels. Her research is supported by grants from NIH, NSF, DOD and other national and international sources.

Research Interest

Biopharmaceutics; nanotechnology; molecular targeting; antisense oligonucleotides

Publications

  • Yin, PT, Shah, S, Pasquale, NJ, Garbuzenko, OB, Minko, T, Lee, KB. Stem cell-based gene therapy activated using magnetic hyperthermia to enhance the treatment of cancer. Biomaterials. 2016;81 :46-57. doi: 10.1016/j.biomaterials.2015.11.023. PubMed PMID:26720500 PubMed Central PMC4715938

  • Dorrani, M, Garbuzenko, OB, Minko, T, Michniak-Kohn, B. Development of edge-activated liposomes for siRNA delivery to human basal epidermis for melanoma therapy. J Control Release. 2016;228 :150-158. doi: 10.1016/j.jconrel.2016.03.010. PubMed PMID:26965957

  • Savla, R, Minko, T. Nanoparticle design considerations for molecular imaging of apoptosis: Diagnostic, prognostic, and therapeutic value. Adv. Drug Deliv. Rev. 2017;113 :122-140. doi: 10.1016/j.addr.2016.06.016. PubMed PMID:27374457

  • Sapiezynski, J, Taratula, O, Rodriguez-Rodriguez, L, Minko, T. Precision targeted therapy of ovarian cancer. J Control Release. 2016;243 :250-268. doi: 10.1016/j.jconrel.2016.10.014. PubMed PMID:27746277 PubMed Central PMC5191987

  • Garbuzenko, OB, Ivanova, V, Kholodovych, V, Reimer, DC, Reuhl, KR, Yurkow, E, Adler, D, Minko, T. Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s). Nanomedicine. 2017;13 (6):1983-1992. doi: 10.1016/j.nano.2017.04.005. PubMed PMID:28434932 PubMed Central PMC5546883

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