Leonard Moise

Biography

    Lenny Moise is Director of Vaccine Research at EpiVax, Inc. Dr. Moise received his PhD from the Department of Molecular and Cellular Biology and Biochemistry at Brown University in Providence, RI in 2002. His research in Dr. Edward Hawrot’s laboratory focused on structure-function relationships of snake neurotoxin interactions with the nicotinic acetylcholine receptor. Dr. Moise’s postdoctoral training at Brown University involved functional analysis of toxin binding sites engineered into toxin-insensitive ion channels. In 2005, he joined Dr. Anne De Groot’s laboratory at Brown University as an Instructor in Medicine in the Department of Medicine (Infectious Disease) to study T-cell epitope-driven vaccination and protein therapeutic immunogenicity. Dr. Moise joined EpiVax, Inc. in Providence, RI in 2006 where he is currently Director of Vaccine Research. He leads T-cell epitope-driven vaccine development projects using a genomes-to-vaccine approach that combines cutting edge immunoinformatic and immunologic methods. Additionally, his research efforts include deimmunization of protein therapeutics by epitope modification. In 2008, Dr. Moise accepted a part-time appointment as Assistant Research Professor in the Department of Cell and Molecular Biology at the University of Rhode Island. He is a founding faculty member of the URI Institute for Immunology and Informatics, where he leads vaccine and immunotherapeutic development projects. Dr. Moise has published over 40 manuscripts and reviews and is supported by funding from the NIH and the American Thyroid Association.  

Research Interest