Felix Amissah
Assistant Professor
Pharmacology
Ferris State University
United States of America
Biography
Prof. Felix Amissah was awarded with Doctor of Philosophy in Pharmaceutical Sciences (Pharmacology/Toxicology), Florida Agricultural and Mechanical University, Tallahassee, FL, 2013 Master of Philosophy (Pharmacology), Kwame Nkrumah University of Science and Technology Kumasi, Ghana, 2004 Bachelors of Pharmacy (Hons), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, 2000.
Research Interest
Prof. Felix Amissah, research interest is in the area of cancer therapeutics and interfaces aspects of molecular cancer biology, biochemistry, drug discovery and pharmacology of small molecules against lung cancers with specific mutations that present treatment challenges. Some of the most deadly cancers are due to mutations in the genes of proteins such as K-Ras and overexpression of Cyclooxygenase-2 (COX-2). His work is aimed mainly at finding the molecular "Achilles heels" of these forms of cancers and utilizing natural and synthetic agents for chemoprevention as well as contributing to the development of effective cures.
Publications
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Nkembo, A., Ntantie, E., Salako, O., Amissah, F., Poku, R., Latinwo, L., & Lamango, N. (2016). The anti-angiogenic effects of polyisoprenylated cysteinyl amide inhibitors in HUVEC, chick embryo and zebrafish is dependent on the polyisoprenyl moiety. Oncotarget, 5. 2016 Sep 8. Poku RA, Amissah F, Duverna R, Aguilar BJ, Kiros GE & Lamango NS. Polyisoprenylated methylated protein methyl esterase as a putative drug target for androgen-insensitive prostate cancer.ecancer2014, 8:459. Amissah F, Duverna R, Aguilar BJ, Poku RA, Kiros GE & Lamango NS. Polyisoprenylated methylated protein methyl esterase overexpression and hyperactivity promotes lung cancer progression. Am J Cancer Res 2014; 4(2), 116-134. Aguilar, B., Nkembo, A. T., Duverna, R., Poku, R.A., Amissah, F., Ablordeppey, S.Y. & Lamango, N. S. (2014) Polyisoprenylated methylated protein methyl esterase: A putative biomarker and therapeutic target for pancreatic cancer. European Journal of Medicinal Chemistry 81, (23), 323–333. Amissah, F.,Duverna, R., Aguilar, B. J., Poku, R. A. and Lamango, N. S. (2013) Polyisoprenylated Methylated Protein Methyl Esterase Is Both Sensitive to Curcumin and Overexpressed in Colorectal Cancer: Implications for Chemoprevention and Treatment. BioMed Research International 2013, 416534. Woode, E., Amissah, F., Agyapong, G. & Ainooson, G.K. (2013) Myorelaxant Effect of an Alcoholic Extract of Sphenocentrum jollyanum Roots in Rabbit Aortic Strip and Corpus Cavernosum. Pharmacologia, 4, 371-382. Book Chapter: Amissah, F., Poku, R. A., Aguilar, B., Duverna, R., Abonyo, B. O. & Lamango, N.S.,(2013) Polyisoprenylated Methylated Protein Methylesterase: The Fulcrum of Chemopreventive Effects of NSAIDs and PUFAs. In: Advances in Medicine and Biology. in: L.V. Berhardt, (Ed.), Advances in Medicine and Biology, Nova Science Publishers, 2013, ISBN: 978-1-62618-806-8pp. 119-144.
