Tracey Boncher
Professor
Medicinal Chemistry
Ferris State University
United States of America
Biography
Tracey Boncher Ph.D.is a Professor, Medicinal Chemistry,Ferris State University,United States of America. she was awarded Ph.D., Pharmaceutical Sciences: Medicinal Chemistry, Wayne State University, 2003 and B.S., Biology/Chemistry, University of Michigan in 1998.Tracey Taught Courses such as Medical Biochemistry, Drug Actions, Infectious Diseases, Topics in Nutritional Biochemistry.
Research Interest
The goal of the current research in my lab is to use solid phase synthesis to enhance and expand the synthesis and purification of novel Peroxisome Proliferator Activated Receptors (PPAR) gamma/delta dual agonists for the treatment of type II diabetes and Alzheimer’s Disease.
Publications
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Modern Chemistry and Applications, 2013, “Basic Concepts of Using Solid Phase Synthesis to Build Small Organic Molecules Using 2-Chlorotrityl Chloride Resinâ€, Bonkowski, Blake, Wieczorek, Jason, Patel, Mimansa, Craig, Chelsea, Gravelin, Alison, and Boncher, Tracey. Bioorganic & Medicinal Chemistry Letters, 2013, 23(3):873-879. “Design, development and evaluation of novel dual PPAR gamma/delta agonistsâ€, Symon Gathiaka, Gayani Nanayakkara, Tracey Boncher, Orlando Acevedo, Johnaton Wyble, Sagar Patel, Akash Patel, Mary Elizabeth Shane, Blake Bonkowski, Jason Wieczorek, Yinghui Rong, Kevin Huggins, Forest Smith, Rajesh H. Amin. US Pharmacist, May 2012, 37(5): 39-42. “The Pharmacists role in Managing Pain Associated with Ocular Traumaâ€, Dinardo, A. and Boncher, T. Essays in Biochemistry, The polyamines: Small Molecules in the Omics Era, Senanayake, T., Amunugama, H., Boncher, T.D., Casero, R.A., Woster, P.M., 26:77-94 2009 Essays in Biochemistry, 2009, 46:77-94. “Design of Polyamine-based Therapeutic Agents: New Targets and New Directionsâ€, M.D. Thulani Senanayake, Hemali Amungama, Tracey D. Boncher, Robert A. Casero, and Patrick M. Woster. Biochem Soc Trans, 2007, 35 (pt2) 356-63. “Polyamine-based Analogues as Biochemical Probes & Potential Therapeuticsâ€, Boncher, T., Bi,X., Varghese, S., Casero, RA, Woster P.M. Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine specific demethylase inhibitors,Pub.No:US 2007/0208082 A1, Boncher, T., Woster, P.M., Casero R. Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors, 2005, US Patent WO/2007/02/839,PCTIUS2006/03/98. Woster, P.M., Ward, T.D., Casero, Jr R.A. Cancer Chemotherapy & Pharmacology, 2003, 52(5)383-390. “Induction of the PAOh/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cellsâ€, Devereux W., Wang T, Stewart TM, Hacker A., Smith R., Frydman B., Valasinas AL, Reddy VK, Marton LJ, Ward TD, Woster PM, Casero RA. Bioorganic & Medicinal Chemistry Letters, 2003, 13(10)1745-1749. “Piperazinyl-linked fluoroquinolone dimmers possessing potent antibacterial activity against drug-resistant strains of Staphylococcus aureus†Kerns, Robert, Rybak, Michael J., Kaatz, Glen W., Vaka Flamur, Cha, Raymond, Grucz, Richard G, Diwadkar, Veena U. and Ward, Tracey D.
