Florida Gulf Coast University
United States of America
Ph.D. in Synthetic Organic Chemistry; University of North Carolina, Chapel Hill, NC ACS Certified B.S. in Chemistry; Emory University, Atlanta, GA 2006 High School Diploma; Saint Thomas Aquinas High School, Fort Lauderdale, FL
His research is dedicated to advancing the science of chemical synthesis through the development of new synthetic methodologies for the efficient construction of structurally complex, medicinally relevant compounds. The structural motifs and natural product targets studied are selected based on their potential medicinal relevance, especially in regards to unique anti-HIV or anti-cancer activity. Currently, the methodology program focuses on the exploitation of vinylogous reactivity and aryne cycloadditions. An supplemental focus of our group is the large scale syntheses of drugs for Neglected Tropical Diseases, which the World Health Organization has put as one of their highest priorities. These projects will likely lead to fruitful collaboration with groups in biology, computational chemistry, and medicine.
Boyce, G. R.; Johnson, J. S. “An Asymmetric Vinylogous Michael Cascade of Silyl Glyoximides, Vinyl Grignard, and Nitroalkenes via Long Range Stereoinduction.” J. Org. Chem. 2016, 81, 1712-1717. Highlighted in Synfacts, 2016, 12, 0409.
Williams, J. D.; Yazarians, J. A.; Almeyda, C. C.; Anderson, K. A.; Boyce, G. R. “Detection of the Previously Unobserved Stereoisomers of Thujone in the Essential Oil and Consumable Products of Sage” J. Agric. Food Chem., 2016, 64, 4319-4326.
Yazarians, J. A.; Jiménez, B. L.; Boyce, G. R. “A regioselective etherification of pyridoxine via an ortho-pyridinone methide intermediate” Tetrahedron Letters, 2017, 58, 2258-2260.