Carroll, David
Associate Professor
Biological Sciences
Florida Institute of Technology
United States of America
Biography
Director of Graduate Programs in Biological Sciences, Florida Institute of Technology, Melbourne, FL. 2010 - present Associate Professor, Department of Biological Sciences, Florida Institute of Technology, Melbourne, FL. 2005 - present Assistant Professor, Department of Biological Sciences, Florida Institute of Technology, Melbourne, FL. 1999 - 2005 NIH NRSA Postdoctoral Research Fellow with Dr. Kathy Foltz, Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA. 1997 - 1999 Associate Editor BMC Developmental Biology 2008 - present
Research Interest
Molecular mechanisms that regulate oocyte maturation and fertilization. Sperm-egg fusion initiates a transient increase in the concentration of cytoplasmic calcium in the egg. This increase is a fundamental process that occurs in the eggs of all the organisms that have been studied and it is critical for activating the egg to begin development. Incredibly, the molecular mechanism that links the sperm-egg interaction to the initiation of this calcium increase is only now beginning to be understood.
Publications
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Carroll, D.J. and Wei, H. (2009) Combining Microinjection and Immunoblotting to Analyze MAP Kinase Phosphorylation in Single Starfish Oocytes and Eggs. Methods Mol. Biol. 518, 57 -66.
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Stricker, S.A., Carroll, D.J., Tsui, W.L. (2010) Roles of Src Family Kinase signaling and the first cell cycle in the marine protostome worm Cerebratulus. Int. J. Dev. Biol. 54:787-93.
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McGinnis, LK, Carroll, DJ, Kinsey, WH (2011) Protein tyrosine kinase signaling during oocyte maturation and fertilization. Mol. Reprod. Dev. 78:831-45.
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Cihal S, Carroll DJ. (2014) Biotinylation of oocyte cell surface proteins of the starfish Patiria miniata. Methods Mol Biol. 1128:197-209.