Jeffrey R. Peterson
Department of Cancer Biology
Fox Chase Cancer Center
United States of America
Biography
Jeffrey R. Peterson,Educational Background: PhD, Cell Biology, Yale University, New Haven, CT, 1997. BA, Biology, Swarthmore College, Swarthmore, PA, 1991. Memberships: American Association for Cancer Research. American Society for Cell Biology. Honors & Awards: American Cancer Society Research Scholar, 2008. American Association for Cancer Research Career Development Award, 2006. NIH Postdoctoral Fellow, 1998-2001. John Enders Grantee, Yale University, 1997. Fulbright Fellow, University of Heidelberg, Germany, 1991-1992. Merck Corporation Research Fellow, 1990.
Research Interest
Cancer Signaling and Metabolism. Identifying and targeting metabolic weakness of triple negative breast cancer. Understanding how cancer cell signaling impacts cell metabolism. Controlling abberant cancer signaling and metabolism through the development and characterization of new drug-like small molecules.
Publications
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Strochlic, T. I., Viaud, J., Eberwine, R. A., Wong, L. E., Minden, A., Turk, B. E., ... & Peterson, J. R. (2012). Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking. Proceedings of the National Academy of Sciences, 109(11), 4116-4121.
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Fink, L. S., Beatty, A., Devarajan, K., Peri, S., & Peterson, J. R. (2015). Pharmacological profiling of kinase dependency in cell lines across triple-negative breast cancer subtypes. Molecular cancer therapeutics, 14(1), 298-306.
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Xu, Q., Malecka, K. L., Fink, L., Jordan, E. J., Duffy, E., Kolander, S., ... & Dunbrack Jr, R. L. (2015). Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases. Science signaling, 8(405), rs13-rs13.
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Duong-Ly, K. C., Devarajan, K., Liang, S., Horiuchi, K. Y., Wang, Y., Ma, H., & Peterson, J. R. (2016). Kinase inhibitor profiling reveals unexpected opportunities to inhibit disease-associated mutant kinases. Cell reports, 14(4), 772-781.
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Kurimchak, A. M., Shelton, C., Duncan, K. E., Johnson, K., Brown, J., O’Brien, S., ... & Connolly, D. C. Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer.
