Paul Cairns
Department of Cancer Research
Fox Chase Cancer Center
United States of America
Biography
Paul Cairns , Educational Background: Postdoctoral Fellowship with Dr. David Sidransky, Johns Hopkins Hospital, Baltimore PhD, Clinical Cancer Genetics, University of Birmingham, UK Membership: Breast Cancer TRDG Member Kidney, Bladder, and Prostate Cancer TRDG Member Ovarian and Gynecologic Cancer TRDG Member
Research Interest
Epigenomics for the Stratification of the Aggressive Potential of Small Renal Masses and RCC. Ultra-Deep Sequencing of p53 Mutation in Blood for Early Detection of Curable Ovarian Cancer. Characterization and Biology of a Novel Molecular Subgroup of HGS Ovarian Cancer. Methylation and Sequence Mutation for Prediction of Risk of Breast Cancer in Women with Benign Disease or DCIS. Identification of an Epigenetic Signature for Progression in Superficial Urothelial Cancer.
Publications
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Hoffman, A. M., & Cairns, P. (2011). Epigenetics of kidney cancer and bladder cancer. Epigenomics, 3(1), 19-34.
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Brooks, J. D., Cairns, P., Shore, R. E., Klein, C. B., Wirgin, I., Afanasyeva, Y., & Zeleniuch-Jacquotte, A. (2010). DNA methylation in pre-diagnostic serum samples of breast cancer cases: results of a nested case–control study. Cancer epidemiology, 34(6), 717-723.
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Potapova, A., Hoffman, A. M., Godwin, A. K., Al-Saleem, T., & Cairns, P. (2008). Promoter hypermethylation of the PALB2 susceptibility gene in inherited and sporadic breast and ovarian cancer. Cancer research, 68(4), 998-1002.
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Cairns, P. (2007). Gene methylation and early detection of genitourinary cancer: the road ahead. Nature reviews. Cancer, 7(7), 531.
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De Caceres, I. I., Dulaimi, E., Hoffman, A. M., Al-Saleem, T., Uzzo, R. G., & Cairns, P. (2006). Identification of novel target genes by an epigenetic reactivation screen of renal cancer. Cancer research, 66(10), 5021-5028.
