Wen-chi Chang
Department of Cancer Research
Fox Chase Cancer Center
United States of America
Biography
Wen-Chi Chang,Educational Background: PhD, Nutrition, Texas A&M University, College Station, TX, 1997. MS, Nutrition, Texas A&M University, College Station, TX. 1992 BS, Nutrition, Providence University, Taiwan , 1988.
Research Interest
Examining molecular alterations underlying colitis-associated colorectal carcinogeneisis in a mouse model of induced colitis. Assessing the ability of chemopreventive agents to inhibit tumor formation in vivo and to modulate biomarker levels in select tissues. Examining the feasibility of using novel image probes to detect colonic adenomas.
Publications
-
Lubet, R. A., Clapper, M. L., McCormick, D. L., Pereira, M. A., Chang, W. C., Steele, V. E., ... & Grubbs, C. J. (2012). Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers. Oncology reports, 27(5), 1400-1406.
-
Li, N., Xi, Y., Tinsley, H. N., Gurpinar, E., Gary, B. D., Zhu, B., ... & Moyer, M. P. (2013). Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Molecular cancer therapeutics, 12(9), 1848-1859.
-
Chang, W. C. L., Zenser, T. V., Cooper, H. S., & Clapper, M. L. (2013). Differential response of flat and polypoid colitis-associated colorectal neoplasias to chemopreventive agents and heterocyclic amines. Cancer letters, 334(1), 62-68.
